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Can we live robustly until our last breath? Do we have to suffer from debilitating conditions and sickness? Is it possible to add more vibrant years to our lives? In The End of Illness, David B. Agus, MD, one of the world’s leading cancer doctors, researchers, and technology innovators, tackles these fundamental questions, challenging long-held wisdoms and dismantling misperceptions about what “health” means. With a blend of storytelling, landmark research, and provocative ideas on health, Dr. Agus presents an eye-opening picture of the human body and all of the ways it works—and fails—showing us how a new perspective on our individual health will allow each of us to achieve that often elusive but now reachable goal of a long, vigorous life. When Dr. Agus decided to pursue a career in oncology, many of his mentors questioned his choice. Why, they asked, would a promising young doctor want to enter a field known for its inescapably grim outcomes? But it was precisely the lack of progress that inspired Dr. Agus to join the war on cancer. He moved away from the modern methods of the medical establishment, which aim to reduce our afflictions to a single point. Instead, as he does in this book, Dr. Agus argues for the adoption of a systemic view—a way of honoring our bodies as complex, whole systems. This outlook informs how we can avoid all illnesses—not just cancer. Dr. Agus empowers us to take charge of our individual health in personal, customized ways we could not have imagined before. This indispensable book is not only a manifesto—a call for revising the way we think about health—it’s also filled with practical but impossible-to-ignore suggestions, including: • How taking multivitamins and supplements could significantly increase our risk for cancer over time. • Why sitting down most of the day, despite a strenuous morning workout, can be as bad as or worse than smoking. • How sneaky sources of daily inflammation—from high heels to the common cold—can lead to a fatal heart attack, and even rob us of our sanity. • How three inexpensive medications—aspirin, statins, and an annual flu vaccine—can substantially change the course of our health for the better. • How taking shortcuts to health via blending fruits and vegetables, and sometimes even by purchasing what we think is “fresh,” could be shortchanging our health. • The single most important thing we can do today to preserve our health and happiness that costs absolutely nothing. Dr. Agus also offers insights and access to breathtaking and powerful new technologies that promise to transform medicine in our generation. In the course of offering recommendations, he emphasizes his belief that there is no “right” answer, no master guide that is “one size fits all.” Each one of us must get to know our bodies in uniquely personal ways, and he shows us exactly how to do that so that we can individually create a plan for wellness. The End of Illness is a bold call for all of us to become our own personal health advocates, and a dramatic departure from orthodox thinking. This is a seminal work that promises to revolutionize how we live.
I've never studied biology, so all of his explanations on cellular mechanics were deeply fascinating.His statistical analysis was thorough for debunking health myths. For example: vitamin supplements are either useless or potentially harmful. First world inhabitants don't die of scurvy. Most "studies" demonstrating the benefits of vitamin supplements don't correct for lurking variables like wealth and health-consciousness. Double-blind placebo-controlled large scale studies over long periods demonstrate most vitamin supplements to actually increase the risk of cancer.Unfortunately, his statistical analysis was much less thorough for supporting his own recommendations. The most difficult to swallow for me is that sitting still at a desk all day is more hazardous to your health than smoking -- and 30 min of vigorous exercise in the morning does not negate this. We need to move all day long. I trust him, but I'd like to see more data to back up the severity of this claim.More fascinating things I learned:Genes are static and proteins are dynamic, so studying proteins would be a much more effective method of diagnosing health issues than studying genes.There are more cells in our body that are not human than there are human. These "guest colonies" fall into distinct classes, differ from person to person, and are not correlated to race, sex, or geographic location. These organisms affect our digestion, and they may be as significant to our health as blood types.Our bodies are chemical factories that break down the incoming food and use it to rebuild ourselves constantly. We get new skin every month, a new liver every six weeks, and new bones every three months. All of this is literally built from the stuff we eat, so that forced me to really think differently about the purpose of food!Ten years ago, only two states had an obesity rate over 20%. Now it's 49 states plus DC. At no point in history have this many people been this overweight. We have no idea how bad of a heart-disease and diabetes epidemic is going to be upon us shortly.Our body can only handle so much inflammation before it stops working. Every flu, every bruise, and every cut adds to this lifetime inflammation tally (which can be read in the proteins). The recommendation: wear comfortable shoes.Cancer is a verb, not a noun. Cancer is not an invader to be carved out or radiated. Cancering is what your body does when the very normal and constant process of cell creation malfunctions. Therefore, it is not unreasonable to believe that the proteins (our body's internet) affect the rate of cancering. If this is true, the "cure for cancer" would be to read your very specific and always changing protein map, and alter your diet (with real foods -- not artificial supplements that are chemically altered and are not absorbed correctly by the body) to specifically meet the issues that you are facing right now. Rapid advances in technology provide hope that this cure is not very far into our future.
